This may increase your risk of side effects, such as chest pain and heart attack. If you no longer need to take this medication, your care team will lower the dose slowly over time to decrease the risk of side effects. Learn about common and serious Propranolol side effects, who's most at risk, how to manage them, and when to call your doctor right away. Learn about the side effects of propranolol, from common to rare, for consumers and healthcare professionals. Clinical data suggests that most common side effects appear soon after starting propranolol regardless of the dose. However, once daily doses exceed 160 mg (particularly when split into individual doses above 80 mg), fatigue, lethargy, and vivid dreams become notably more frequent. NHS medicines information on propranolol – what it's used for, side effects, dosage and who can take it. What are the most common side effects of propranolol? The most common side effects of propranolol are listed below. Tell your healthcare provider if you have any of these side. Propranolol appears in the blood after 30 minutes and has a maximum effect between 60 and 90 minutes when taken orally. [10][14] Common side effects include nausea, abdominal pain, and constipation. [10] It may worsen the symptoms of asthma. [10] Some conditions may become worse when the medicine is stopped suddenly, which can be dangerous. Propranolol will add to the effects of alcohol and other central nervous system (CNS) depressants. CNS depressants are medicines that slow down the nervous system and may cause drowsiness. The most common side effects of propranolol are feeling tired, cold hands and feet, disturbed sleep, and stomach upset. Propranolol is a beta-blocker medicine used for conditions like high blood pressure, angina, and anxiety symptoms. It works by slowing down your heart's activity, reducing blood pressure and heart rate. Read on to learn the common and rare side effects for propranolol, and when to reach out to your healthcare team for further guidance.